The article, Specific Regularities of Constructing and Reproducing Human Interrelations (the Historical, Philosophical, and Psychological Aspects), is focused on discussing the new methodological approach, from the terms of Synergetic Historicism, to the study on the phenomenon of Human relationships. The investigation in question is based on the results of analysing historical, philosophical, and psychological aspects of the problem considered by some investigators as that of dynamic transformations of the nature of interrelationship between conscious subjects as well as of its reproduction specifics. The Method of Dual Oppositions and the Law of Self-organizing Social-cum-Cultural Ideals, applied to the investigation, allowed to rethink phenomena of human interrelations as a special and unique ability of society members (who are regarded as products of the synthesis of ideological, social, and value-animals) for being incorporated into interrelations with those standing for spiritual values, on the one hand, and those standing for utilities, on the other. The author believes that the process of reproducing by society members models of establishing human interrelations is defined by the factor of selecting alternative ways of Self-determination which are based on the constructive or destructive approaches to the problem of Freedom and Responsibility. In this manner, if the constructive approach is aimed at transforming Self-developing subjects into Self-determining ones, taking part of constructing social and interhuman relations in the course of establishing a social and cultural space common to all mankind, then the destructive approach is characterized by transforming Seif-developing subjects into Self-destructive ones, aimed at antihumanistic principles as well as at the approaching moment of Technological Singularity and the transition to the Post-Human reality.