The article deals with the development of stress resistance in the training of students of transport universities on high-tech training equipment. The research into the problem of students’ stress resistance, which is aimed at ensuring the successful achievement of learning objectives and is realized by means of shaping behaviors, is analyzed. The notion of stress resistance in training with high-tech training equipment is formulated. Possible positive and negative psychological reactions of trainees during training on high-tech simulators have been considered. The findings of stress tolerance self-assessment test. The conclusions are drawn up regarding the possibility of stress resistance development in the process of training on high-tech training equipment in combination with a complex of self-regulation exercises which is aimed at neuromuscular relaxation, reflexive thinking development and reduction of emotional tension.