The factor structure of resilience, coping strategies and victimization of adolescents with chronic diseases (oncology — 61, rheumatic diseases — 51, cerebral palsy — 51) and conventionally healthy (n = 86) was analyzed. The study used the S. Muddy Resilience Test modified by D. A. Leontiev and E. I. Rasskazova, the SORET R. Carver questionnaire adapted by E. I. Rasskazova, T. O. Gordeeva and E. N. Osin, and the questionnaire “Type of role victimization” by M. A. Odintsova and N. P. Radchikova. Significant differences on many scales between the four groups are shown. The factor structure of resilience and coping of adolescents of four groups was revealed, the features of resilience in connection with coping strategies and victimization of adolescents suffering from oncological, rheumatological diseases and with cerebral palsy were analyzed in connection with the tasks of psychological assistance. The relationship between resilience and victimhood is shown, limitations are discussed and prospects for research are outlined.