The article considers a set of measures that ensure the successful formation of technological competence in students. Fundamental aspects of the formation of technological skills are revealed using the example of acquiring experience in the interaction of radiation and matter. This includes theoretical and practical education, scientific research and the application of knowledge in real projects. The competency-based approach is the basis for determining the ways and conditions for increasing the effectiveness of the formation of technological competence in students, as well as the optimal solution of professional problems by graduates using various technologies. Taking into account modern approaches to improving the process of forming technical skills in students in the field of research into the interaction of radiation and matter, the article lays the foundation for further developments in this area.